别名: Tapazole, Thiamazole
CAS 60-56-0 分子式 C4H6N2S 分子量 114.17
靶点: Thyroid peripheral conversion;
Methimazole is a thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.